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KMID : 0361020220650060358
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Korean Journal of Otolaryngology - Head and Neck Surgery
2022 Volume.65 No. 6 p.358 ~ p.361
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A Case of Neuromyelitis Optica Spectrum Disorder of a Patient Who Present for Fungal Sinusitis
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Seo Jun-Won
Jeong Do-Yoon
Kim Hye-Jeen
Choi Ji-Yun
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Abstract
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Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system, characterized by repeatedly invading the brain, optic nerve, or spinal cord. In 2004, when a disease-specific antibody (aquaporin-4-immunoglobulin G) was discovered in the se- rum of an optic neuromyelitis patient, it was thought to be a separated disease from multiple sclerosis. Since 2004, however, the concept of the disease has been expanded to include NMO spectrum disorder (NMOSD). We experienced a rare case of NMOSD in a patient who pre- sented with left visual disturbance and underwent endoscopic sinus surgery because of acute fungal sinusitis. We report this case with a review of the literature.
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KEYWORD
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Anti-aquaporin 4 autoantibody, Fungal, Neuromyelitis optica, Optic neuritis, Sinusitis
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